Effects of 6 Weeks of Aerobic Training and Fenugreek Extract Administration on Plasma Apo A-I of Female Patients with Type 2 Diabetes

Abstract

Purpose: Fenugreek, as an herbal plant, can significantly increase Apo A-I, an important factor in 
preventing cardio vascular diseases among diabetic patients, which is a major cause of their mortality. 
Considering that exercise activities have a positive effect on diabetic patients, this study aimed to investigate 
the effects of 6 weeks of aerobic training and fenugreek administration on Apo A-I levels of diabetic women. 
Material and Methods: Thirty diabetic women volunteered to take part in the present study and were 
randomly placed into three groups: aerobic training (Group 1), aerobic training+ fenugreek administration
(Group 2) and control group (Group 3). Aerobic training group exercised for 6 weeks, at 60-75 %of their 
maximal heart rate. Blood sampling was done before and after the trial. 
Results: There was a significant decrease in weight, body fat percent, BMI and fasting blood sugar, and a 
significant increase in Apo A-I, HDL and HDL/LDL ratio (p<0.001) in the groups 1,2. A significant decrease 
was also observed in TG levels of group 1. Increased level of LDL was the only significant change observed in 
the control group. Total cholesterol and HDL/LDL ratio of group 2 decreased and increased, respectively, as
compared to group 1 (p<0.05). 
Discussion and Conclusion: Fenugreek extract along with aerobic training can be useful in increasing levels 
of Apo A-I and lowering LDL levels in diabetic patients

Keywords

• Aerobic training
• T2DM
• Apo A-I

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