The Effect of Eight Weeks of Aerobic Training on the Plasma Levels of Adipokines in Postmenopausal Middle-Aged Women

Document Type : Original Article

Abstract

Physical activity is a known modifiable lifestyle means for reducing postmenopausal disease risks, but the 
relevant biological mechanisms are not well understood. Metabolic factors may be involved. In this study, we 
aimed at determining the effects of 8weeks of an aerobic training program on plasma levels of adiponectin and 
leptin in Postmenopausal middle-aged Women. For this purpose, twenty middle-aged healthy Women were selected and assigned in two equal groups of experimental and control based on their body fat percentage. The 
experimental group participated in 8weeks of aerobic training, 4 days a week in alteration days, at the 65-75 
percent of maximum heart rate, but the control group remained sedentary. Blood samples were collected prior 
to and after the training program for all subjects and plasma adipokines levels were measured. Results showed 
a decrease in leptin concentrations but significant increase in adiponectin concentrations, following 8weeks of 
the aerobic training program (p<0.001). In addition, reduction in body fat percentage (p<0.001) negatively correlated with adiponectin (p<0.001) but positively correlated with leptin changes (p<0.001). In postmenopausal 
middle-aged women, 8weeks of aerobic training reduced body fat percentage and improved plasma adipokines 
levels, so aerobic training can be considered as an effective way for preventing obesity and associated diseases. 

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